International Seminar on “Molecular Biology”
Principal, , HOD, Biotechnology and other members of Staff welcomed the Chief Guest. Principal formally welcomed the Chief Guest, dedicated this Seminar to 102nd Birth-Anniversary of Shaheed-e-Azam Bhagat Singh, who strongly advocated the vast spread of quality education and creation of new knowledges by the youth of
Prof. Y. Chang discussed the ultra modern Molecular approaches on the development of Johne’s Disease or Paratuberculosis Vaccine. Prof. Chang briefly introduced the audience with the global importance of Paratuberculosis and its zoonotic concerns. As the disease is important not only for economic concerns but also for human health concerns hence development of efficacious vaccine is the must requirement of today’s world in order to secure economic losses and to reduce human exposure to this deadly pathogen. First of all he discussed the use of recombinant Ag85 complex, SOD, 74F Poly Protein etc. as Vaccine candidate in goat and cattle system. The recumbinent antigens were able to significantly raise the immune system of animals and hence the protectivity. He laid the concept of cocktail antigens as potent vaccine candidates. Secondly he discussed the attenuated mutant strain of Mycobacterium avium subspecies paratubnerculosis (MAP). The mutants used by were leuD deficient. These mutants were unable to cause disease but raise the immune system of animal significantly. Hence he laid stress on the use of these mutants as vaccine candidates. Finally he discussed the use of recombinant Salmonella typhimurium expressing MAP antigens as vaccine candidate. He emphasize that this approach can meet the cost constraints of the recombinant antigens. In conclusion he laid stress on the molecular vaccine to control disease.
He appreciated the entire infrastructure of
The scientific session was followed by the cultural session by students of Biotechnology Department, wherein Ana, Rajwinder, Swati, Poonam, Surabhi, Rupinder, Iti and Niti performed traditional Giddha. Priyanka performed Katthak Dance in honour of the international guest. The DAV College Managing Committee, Staff and Students wished Professor Chang new heights of success in controlling the John’s Disease through the development of efficient vaccine which should further lead to treatment of other diseases amongst the humans and the animals.


